The right dose at the right time is critical for any patient living with a disease. Precision dosing has become a widely discussed topic, and a growing literature recognizes the implications of imprecise dosing on public health, related to both cost…
For patients living with inflammatory bowel disease (IBD), Infliximab (IFX), a monoclonal antibody, has emerged as an efficient treatment for disease activity reduction and IBD patient life quality improvement. However, while IFX is an effective treatment for some patients, a…
Pediatric inflammatory bowel disease (IBD) is a debilitating chronic condition that affects the gastrointestinal tract of children. The symptoms are similar to adults with IBD, but due to the developing immune system, pediatric patients have different needs than adults when…
Blood tests are critical in the medical field for a variety of reasons. Specifically, blood tests can help doctors evaluate how well the organs are working, diagnose diseases, and assess how well your blood is clotting. In addition, a blood…
Baysient’s web-based applications, iDose and T3 were specifically developed to facilitate the dosing of biological agents by integrating real patient’s clinical characteristics. Both softwares use Bayesian models, routine lab results, and demographics to individualize dosing to a specified target trough…
IV Infliximab, a monoclonal antibody, has emerged as an efficient treatment with many clinical benefits, such as quick disease activity reduction and IBD patient life quality improvement. However, drug development of infliximab using weight-based dosing of MAbs without consideration of…
Dr. Marla Dubinsky discusses the unique, personalized, and integrated care offered for children at the Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center in a video posted by Mount Sinai Health System. Dr. Dubinsky starts by discussing some…
Ankylosing Spondylitis Awareness Month is observed every April. This month is dedicated to raising awareness and recognizing arthritis and other associated illnesses such as ankylosing spondylitis. What is Ankylosing Spondylitis? Ankylosing spondylitis, or AS, is a form of arthritis that…
The right dose of medicine is crucial when it comes to the treatment process. For patients with inflammatory bowel disease (IBD), the wrong dose can cause patients to lose response to Infliximab (IFX), a highly effective drug used to treat…
Precision dosing focuses on the individualization of drug treatment regimens based on drug attributes, pharmacokinetic/pharmacodynamic variability, disease state characteristics, and patient-specific factors. Before precision dosing, pharmaceutical medicine adopted a one-size-fits-all approach that focused on dosing regimens based on the average…
